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GC-MS-AMDIS结合保留指数分析藿香挥发油

Analysis of the Chemical Composition of Volatile Oil from Agastache rugosa by GC-MS-AMDIS Based on Retention Index

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【作者】 任恒鑫张舒婷吴宏斌任钰迪邹韬博孙长海

【Author】 REN Heng-xin;ZHANG Shu-ting;WU Hong-bin;REN Yu-di;ZOU Tao-bo;SUN Chang-hai;College of Pharmacy,Jiamusi University;C ollege of Pha rmacy,Heilongjiang University of Chinese Medicine;

【机构】 佳木斯大学药学院黑龙江中医药大学药学院

【摘要】 以吉林省产藿香为研究对象,采用水蒸气蒸馏法提取藿香中挥发油,利用气相色谱-质谱(GC-MS)联用法和自动质谱退卷积定性系统(AMDIS),结合程序升温保留指数(PTRI)对提取的挥发油成分进行分析,采用峰面积归一化法确定各组分的相对含量,结果共分离出168种化学成分,鉴定出其中46种,占挥发性物质总峰面积的91.72%,主要成分有脱氢香薷酮(47.65%)、胡椒酚甲醚(15.01%)、香薷酮(6.16%)、蛇麻烯(5.74%)、n-十六酸(2.47%)、亚麻酸(1.84%)等。

【Abstract】 The volatile oil in Agastache rugosa from Jilin province, China was extracted by steam distillation and analyze d by gas chromatography-mass spectrometry with automated mass spectral deconvolut ion and identification system(GC-MS-AMDIS) based on the temperature-programmed re te ntion in dex(PTRI). The relative concentration of each component was determined by peak area normalization. A total of 168 compounds were isolated, of which 46 compounds were chemically identified and accounted for 91.72% of the total peak area. The major components identified were dehydroelsholtzia ketone(47.65%), methyleugenol(15.01%), elsholtzia ketone(6.16%), humulene(5.74%), n-hexadecanoic acid(2.4 7%), and linolenic acid(1.84%).

【基金】 黑龙江省自然科学基金面上项目(D201226);黑龙江省卫生厅科研课题(2011-445)
  • 【分类号】R284
  • 【被引频次】28
  • 【下载频次】430
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