【摘要】 将表没食子儿茶素没食子酸酯(EGCG)和大豆卵磷脂溶于无水乙醇,制备EGCG磷脂复合物,利用紫外扫描、红外光谱、X射线衍射、差示扫描量热分析等方法对其结构进行表征,并对该复合物的表观油水分配系数进行测定。结果表明:该实验条件下EGCG和磷脂通过非共价键结合得到目标复合物;表观油水分配系数的分析结果表明EGCG磷脂复合物能够改善EGCG的脂溶性。更多还原

【Abstract】 In this study,EGCG-phospholipid complex was prepared through the dissolution of EGCG and soybean lecithin in ethanol,and its structure was characterized by UV spectroscopy,IR spectroscopy,X-ray powder diffractometry and differential scanning calorimetry.Meanwhile,the apparent water/n-octanol partition coefficient of this complex was determined.The results showed that non-covalent bonding between EGCG and phospholipid under experimental conditions generated the target complex.Furthermore,the solubility of EGCG was improved according to apparent partition coefficients of EGCG and EGCG-phospholipid complex in n-octanol buffer solution system.更多还原