Objective:To study anti-tumor activities of the glycosaminoglycan extracted from Pinctada martensii Dunder. Methods:MTT assay was used to determine the inhibition effects of the glycosaminoglycan called PGI and PGII extracted from Pinctada martensii Dunder on proliferation of human Hela cell,L1210 cell and K562cell in vitro, and the ratio of extending viability on the L1210 tumor- bearing mouse caused by the glycosaminoglycan extracted from Pinctada martensii Dunder was examined in vivo. Results:MTT showed ...