【摘要】 [目的]了解母婴的麻疹野病毒中和抗体水平及其相关性。[方法]采用中和试验的方法直接检测孕妇及新生儿的麻疹野病毒中和抗体水平并进行相关分析。[结果]孕妇及新生儿的麻疹野病毒中和抗体阳性率分别为91.52%和88.57%,平均几何滴度(GMT)分别为61.32和58.17;配对母婴的麻疹野病毒中和抗体水平呈高度正相关(r=0.899,P<0.01)。当母体的抗体滴度≥1∶16时,其子代抗体的阳性率可达100.00%。[结论]母婴的麻疹抗体水平密切相关,提高母源麻疹抗体水平应是控制低月龄小儿麻疹发病的重要措施之一。更多还原

【Abstract】 [Objective] To investigate the level of wild- measles neutralization antibody of both mother and infant,and its correlation between the paired mother and infant. [Methods] The wild-measles neutralization antibody in the serum of the women and their infants were detected directly by a neutralization test( NT) methods. [Results] The positivity rates of neutralization antibody in mothers and their infants were 91. 52% and 88. 57% respectively,geometric mean title of neutralization antiboby( GMT)being 61. 32 and 58. 17 respectively. And the titer of neutralization antibody was highly correlated( r =0. 899,P < 0. 01) between mother and infant in pairs. When the GMT of mother was≥1 ∶ 16,the positivity rate of neutralization antibody in their infants might reach 100. 00%. [Conclusion] It is important to increase the maternal measles antibody level in order to prevent infants from measles.更多还原