【摘要】 目的研究半剂量99mTc-MIBI双时相断层显像在乳腺肿块诊断中的价值。方法选择220例乳腺肿块患者,随机分为半剂量组(99mTc-MIBI注射剂量370 MBq)和传统剂量组(99mTc-MIBI注射剂量740 MBq),行99mTc-MIBI双时相断层显像。分别计算乳腺肿块早期相、延迟相的放射性比值(T/NT),并对乳腺癌的诊断效率进行比较。结果半剂量组良性病变患者早期相T/NT高于延迟相T/NT(P<0.05),恶性病变患者早期相T/NT高于良性病变患者(P<0.05)。传统剂量组良性病变患者早期相T/NT高于延迟相T/NT(P<0.05),恶性病变患者早期相T/NT高于良性病变患者(P<0.05)。两组早期相、延迟相T/NT比较差异均无统计学意义。两组对乳腺癌的灵敏度、特异性、准确性差异无统计学意义。结论半剂量99mTc-MIBI双时相断层显像在乳腺肿块的诊断中具有良好的图像质量,不影响临床疾病的诊断,且辐射剂量减少一半。更多还原

【Abstract】 Objective To study the diagnostic value of half the radiation dose double-phase 99mTc-MIBI tomographic imaging in breast lesions.Methods A total of 220 patients with breast lesions were randomly divided into half the radiation dose group(99mTc-MIBI injected dose was 370 MBq) and the conventional dose group(99mTc-MIBI injected dose was 740MBq).All patients underwent double-phase 99mTc-MIBI tomographic imaging in breast lesions.The early phase and delayed phase of radioactivity ratio(T/NT) of breast lesions were calculated separately,and the diagnostic efficiency of breast cancer was compared.Results The early phase T/NT in half the radiation dose group of patients with benign lesions was higher than the delay phase T/NT(P < 0.05),and the early phase T/NT in patients with malignant lesions was higher than that in patients with benign lesions(P < 0.05).the early phase T/NT in the conventional dose group of patients with benign lesions was higher than the delay phase T/NT(P < 0.05),and the early phase T/NT in patients with malignant lesions was higher than that in patients with benign lesions(P < 0.05).T/NT comparative differences had no statistical significance in two groups between the early phase and the delayed phase(P > 0.05).The sensitivity,specificity and accuracy of breast cancer had no statistically significant difference in two groups(P > 0.05).Conclusion Half the radiation dose double-phase 99mTc-MIBI tomographic imaging in breast lesions has good image quality,and it doesn’t affect the clinical diagnosis and reduce half of radiation dose.更多还原