【摘要】 目的:分析45例腓总神经不全损伤患者复合肌肉动作电位（CMAP）的波幅、时程,探讨其与周围神经损伤程度的关系。方法 :选择2012年1月至2012年12月就诊于我院的45例不同程度腓总神经不全损伤患者,根据患者胫前肌肌力级别将45例患者分为三组（n=15）:胫前肌肌力4-5级（P₁组）、胫前肌肌力2-3级（P₂组）、胫前肌肌力1级（P₃组）。应用肌电诱发电位仪记录45例患者的CMAP波形,测量CMAP波幅与时程。采用SPSS13.0统计软件对数据进行秩和检验,分析各组间CMAP波幅与时程的差别。结果 :（1）P₁组、P₂组和P₃组腓总神经-胫前肌CMAP平均波幅分别为7.1±0.2mv、3.3±0.3mv和0.5±0.1mv;P₂组、P₃组与P₁组相比,波幅均有显著性差异（P<0.05）;P₃组与P₂组相比,波幅亦有显著性差异（P<0.05）。（2）P₁组、P₂组和P₃组腓总神经-胫前肌CMAP平均时程分别为11.4±0.4ms、16.9±0.6ms和23.3±1.2ms;P₂组、P₃组与P₁组相比,时程均有显著性差异（P<0.05）;P₃组与P₂组相比,时程亦有显著性差异（P<0.05）。结论 :（1）CMAP波幅、时程有助于评价周围神经受损的严重程度。（2）CMAP波幅降低提示有功能的周围神经轴突数量减少,时程延长反映了周围神经的脱髓鞘损害。更多还原

【Abstract】 Objective: To analyze the amplitude and duration of CMAP of 45 patients with incomplete peroneal nerve injury and investigate the relationship between CMAP and the degree of peripheral nerve injury.Methods: 45 patients with different degree of incomplete peroneal nerve injury from January 2012 to December2012 were selected. 45 patient were divided into three groups（n = 15）according to the levels of tibialis anterior muscle strength: muscle strength grade 4⁵（group P₁）,muscle strength grade 2³（group P₂）,muscle strength grade 0¹（group P₃）. The CMAP waveforms of all the patients were recorded and the amplitudes and durations were measured using EMG/EP instrument. The CMAP amplitude and duration datas of three groups were analyzed through rank sum test using SPSS13.0 statistical software. Results:（1）The mean peroneal nerve-tibialis anterior muscle CMAP amplitudes of group P₁, P₂and P₃were 7.1±0.2mv, 3.3±0.3mv and 0.5±0.1mv respectively. Compared with group P₁, the CMAP amplitudes of group P₂and P₃were significantly different（P<0.05）. Compared with group P₂, the CMAP amplitude of group P₃was significantly different（P<0.05）.（2）The mean peroneal nerve- tibialis anterior muscle CMAP durations of group P₁,P₂and P₃were 11.4±0.4ms,16.9±0.6ms and 23.3±1.2ms respectively. Compared with group P₁, the CMAP durations of group P₂and P₃were significantly different（P <0.05）. Compared with group P₂, the CMAP duration of group P₃was significantly different（P <0.05）. Conclusions:（1） CMAP amplitude and duration are conducive to evaluate the severity of peripheral nerve injury.（2） The decreased CMAP amplitude suggests the axon number reduction of functional peripheral nerves and the prolonged CMAP duration reflects the demyelination damage of peripheral nerves.更多还原