【摘要】 目的检测成都地区过敏性鼻炎(AR)患者血清中的过敏原情况,为临床诊断和治疗过敏性鼻炎提供实验室依据。方法过敏性鼻炎患者88例及同期就诊的非过敏性鼻炎患者30例,采用酶免疫斑点法,检测患者血清中的吸入性和食入性过敏原共20项。结果吸入性过敏原前3位为:屋尘螨/粉尘螨组合(65.9%)、屋尘(43.2%)狗上皮(9.1%);食入性过敏原前3位为:虾和海鱼组合(13.6%)、艾蒿(11.4%)、黄豆(10.2%)。30例阴性对照仅有1例检测出阳性过敏原为虾和海鱼。结论屋尘螨/粉尘螨和虾/海鱼分别是导致成都地区AR最主要的吸入性和食入性过敏原,有意识地避免接触这些过敏原及进行特异性的免疫治疗对防治过敏性鼻炎具有积极意义。更多还原

【Abstract】 Objective To detect allergen in serum of patients with allergic rhinitis(AR) for diagnosis and treatment.MethodsSera from 88 AR patients and 30 non-allergic rhinitis controls were collected and detected for 20 kinds of allergen by using enzyme-linked immunospot assay.ResultsIn Chengdu city,the positve rates arrangement of top 3 of inhalant allergens are house dust mite/dermatophagoides farinae(65.9%),house dust(43.2%) and dog epithelium(9.1%),respectively and of ingested allergens are shrimp/marine fish(13.6%),artemisia argyi(11.4%) and soybean(10.2%),respectively.Only 1 of 30 controls is allergic to shrimp and marine fish.ConclusionHouse dust mite/dermatophagoides farinae and shrimp/marine fish are the uppermost inhalant and ingested allergens recpectively which induced AR in Chengdu city.Dection of allergen is meaningful for patients to prevent suffering from AR disease by avoiding touching these allergens consciously,and it is important for clinicians to perform specific immunotherapy on AR patients.更多还原