【摘要】 目的探讨高血压病患者微量白蛋白尿(MAU)与血压变异性以及心血管危险因素的关系。方法对2009年7月～2010年7月在心内科住院患者临床资料进行回顾性分析,其中314例患者均做动态血压监测和微量白蛋白尿检测。结果微量白蛋白尿的检出率为55.4%,男女性别间差异无统计学意义,便随年龄增大阳性率显著增加。微量白蛋白尿与高血压病程、血糖、总胆固醇、低密度脂蛋白胆固醇相关。24h动态血压与微量白蛋白尿:随着收缩压变异系数增大,微量白蛋白尿发生率增加(P=0.002),平均收缩压越大发生率越高(P=0.003),舒张压变异系数与微量白蛋白尿发生率无相关性(P=0.96)。结论在高血压病患者中,微量白蛋白尿与血压变异系数、尤其是收缩压变异系数独立相关。更多还原

【Abstract】 Objective To investigate the relationship of microalbuminuria and blood pressure variation and cardiovascular risk factors.Methods We retrospectively analyzed clinical data of patients treated in the department of cardiology between July 2009 and July 2010.Information on microalbuminuria testing and other clinical date were obtained from 314 patients.All patients were monitored by ambulatory blood pressure.Results Microalbuminuria determined was 55.4%,there was no differences between men and women.However,the microalbuminuria was associated positively with age.Increased age was associated with a significantly increased positive rate.Cardiovascular risk factors and microalbuminuria:microalbuminuria was associated with duration of hypertension,fasting blood sugar,tota1 cholesterol.and low density lipoprotein—cholestero1.24 h ambulatory blood pressure and microalbuminuria :the prevalence of microalbuminuria increased with increasing coeficient of systolic variation(P=0.002).There was no correlation between the coeficient of diastolic variation and the prevalence(P=0.96).Conclusion Microalbuminuria is independently associated with coeficient of variation of blood pressure,especially with coeficient of variation of systolic blood pressure.更多还原