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同型半胱氨酸对疾病的诊断价值探讨
The dignostic value of homocysteine
【摘要】 目的探讨血浆同型半胱氨酸(Hcy)水平对几类疾病的诊断价值,并进行对比与评价。方法分别检测冠心病30例、脑血管疾病30例、恶性代谢性肿瘤30例、白血病30例及糖尿病肾病患者30例以及健康体检者30例的Hcy含量,并统计分析六组之间的关系。结果冠心病组,脑血管病组以及糖尿病肾病组的Hcy水平明显高于对照组(P<0.05),并且冠心病组,脑血管病组以及糖尿病肾病组之间Hcy水平差异无统计学意义;恶性代谢性肿瘤组与白血病患者的Hcy水平与健康对照组差异无统计学意义。结论 Hcy是冠心病、脑血管病、糖尿病肾病的危险因素之一,但Hcy是否为恶性肿瘤、白血病的危险因素,以及Hcy能否作为鉴别诊断冠心病、脑血管病及糖尿病肾病等疾病的指标,尚须进一步研究。
【Abstract】 Objective To explore the diagnostic value of the plasma homocysteine(Hcy) in some of diseases,and comparation and evaluation.Methods Detect the Hcy content of each 30 cases of coronary heart disease detection,30 cases of cerebrovascular disease,30 cases of malignant tumor of the metabolic,30 cases of leukemia and 30 cases of the diabetes nephrosis patient and 30 cases of the healthy peaple,and the statistical analysis of the relationship between the six groups.Results The Hcy of coronary heart disease,cerebrovascular disease group and the group of diabetic nephropathy was significantly higher than the control group(P<0.05),The difference of malignant tumor with leukemia patients with the metabolic group and healthy controls was statistically significant.Conclusion Hcy is coronary heart disease,cerebrovascular disease,diabetes kidney disease risk factor,but whether Hcy for malignant tumor,leukemia risk factors,and can be used as Hcy differential diagnosis of coronary heart disease,cerebrovascular disease,and diabetes nephropathy and other disease index,still must further study.
- 【文献出处】 四川医学 ,Sichuan Medical Journal , 编辑部邮箱 ,2013年01期
- 【分类号】R446.1
- 【被引频次】2
- 【下载频次】71