【摘要】 【目的】评价邓铁涛调脾护心法诊疗方案治疗冠心病心绞痛的疗效。【方法】采用前瞻性队列研究,根据治疗意愿将患者分为暴露组与非暴露组,观察期1年。非暴露组采用西医常规治疗,暴露组在西医常规治疗的基础上加用邓铁涛调脾护心法治疗冠心病心绞痛方案,观察期内治疗时间不少于3个月。对治疗前后的中医证候疗效、心绞痛积分与生活质量进行比较。【结果】(1)治疗1年后,暴露组的中医证候疗效显著优于非暴露组,差异有统计学意义(P<0.05)。(2)治疗1年后,2组患者的心绞痛积分均有显著改善,与治疗前比较差异均有统计学意义(P<0.01),且暴露组的改善作用优于对照组,差异有统计学意义(P<0.01)。(3)治疗1年后,2组西雅图心绞痛生存质量量表(SAQ)各个维度评分均有显著改善,除非暴露组的躯体活动受限程度(PL)、疾病认识程度(DP)外,与治疗前比较差异均有统计学意义(P<0.05),且治疗组SAQ各维度评分的改善作用均显著优于对照组,差异均有统计学意义(P<0.01)。【结论】邓铁涛调脾护心法冠心病诊疗方案治疗冠心病心绞痛,能明显改善患者症状,减少心绞痛发作,提高患者生活质量。更多还原

【Abstract】 Objective To observe the therapeutic effect of the therapy of regulating spleen and protecting heart,which is founded by Professor Deng Tietao,for the treatment of angina pectoris induced by coronary artery disease(CHD-AP).Methods A prospective cohort study was carried out in the patients with CHD-AP.According to the intention-to-treat,the patients were divided into exposure group and non-exposure group,and the observation lasted one year.Non-exposure group was given routine western medical treatment,and the exposure group was given the therapy of regulating spleen and protecting heart on the basis of the treatment for the non-exposure group.During the observation period,the treatment lasted over 3 months.The effects on relieving symptoms as well as AP scores and the scores of quality of life evaluated by Seattle Angina Questionnaire(SAQ) were observed in both groups before and after treatment.Results The results of one-year observation showed that exposure group had obvious effect on relieving symptoms(P <0.05 compared with the non-exposure group),AP scores were improved in both groups(P <0.01 compared with those before treatment),and the improvement in the exposure group was superior to that in the non-exposure group(P< 0.01).Except for dimensions of physical limitation(PL) and disease perception(DP) in non-exposure group,the scores of all of the other SAQ dimensions were markedly improved in both groups(P<0.05),and the improvement in the exposure group was superior to that in the non-exposure group(P<0.01).Conclusion The therapy of regulating spleen and protecting heart is effective on relieving symptoms,reducing the frequency of AP attack,and improving quality of life of CHD-AP patients.更多还原