【摘要】 目的了解2006~2009年江门市VCT门诊求询者、综合门诊就诊者和洗浴娱乐场所从业员HIV感染状况,为制定艾滋病预防控制策略提供科学依据。方法对2006~2009年在VCT门诊求询者、综合门诊就诊者及常规体检的洗浴娱乐场所从业员采集血液标本,首先用一种酶联试剂筛查,阳性者再用原有试剂和另一种酶联试剂重复检测,其一为阳性或两者皆阳性定义为"筛查阳性",并应用蛋白免疫印迹(WB)法确证。结果共检测5008人,HIV抗体阳性126人(2.52%),男性94人(4.33%),女性32人(1.13%),性别间差异有显著性(P<0.01),年龄分布50岁以上组高发(P<0.01),2007年阳性率最低,为1.86%,2009年阳性率最高,为3.14%。VCT门诊求询者阳性率为5.62%,性别间差异有显著性(P<0.01),年龄分布50岁以上组高发(P<0.05)。综合门诊就诊者阳性率为1.26%,性别间差异无显著性(P>0.05),年龄分布50岁以上组高发(P>0.05)。洗浴娱乐场所从业员全为女性,阳性1人(0.049%)。不同人群以VCT门诊求询者阳性率较高(P<0.01)。结论江门市VCT在HIV发现方面起着重要作用,但2006~2009年HIV阳性率呈起伏上升趋势,VCT门诊求询者HIV阳性率偏高,属于高度易感人群,今后有必要在高危人群中开展更有针对性的行为干预措施,预防艾滋病的传播扩散。更多还原

【Abstract】 Objective To understand the status of HIV infection among individuals receiving HIV VCT outpatients,those working in baths and public entertainment places in Jiangmen from 2006 to 2009,and provide scientific evidence for formulating HIV/AIDS control strategies.Methods All the serum samples from individuals who received HIV VCT services,outpatients and those working in baths and public entertainment places were tested with ELISA with one reagent,or with two reagents if positive.Samples that was positive in anyone of the two ELISA assays was defined as"screening positive"and confirmed by western blotting.Results Totally 5 008 persons were tested and126 were positive for HIV(2.52%)including 94 males(4.33%)and 32 females(1.13%),showing significant difference(P<0.01.Most of the positives occurred to age groups of over 50 years(P<0.01),the lowest positive rate was 1.86% in 2007 and the highest was 3.14% in 2009.The positive rate of HIV antibody among individuals who received HIV VCT services was 5.62%,the positive rate of HIV antibody showed significant difference between male and female(P<0.01).The positive rate of HIV antibody among outpatients was 1.26%,the positive rate of HIV antibody did not show significant difference between male and female(P>0.05),most of the positive cases occurred to age groups of over 50 years(P>0.05).One positive was detected from the females working in public baths and entertainment places(0.0049%).Conclusions VCT plays an important role in HIV identification in Jiangmen,but the positive rate of HIV antibody showed a fluctuant upward trend from 2006 to 2009,the positive rate of HIV antibody of individuals who received HIV VCT services was high in Jiangmen from 2006~2009,Thus it is necessary to conduct target behavioral intervention among the high risk population groups to prevent the transmission of AIDS in this area.更多还原