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螺内酯联合芪参益气滴丸治疗心肌病并心力衰竭疗效观察

Effect of spironolactone combined with Qishenyiqi pills on 60 dilated cardiomyopathy cases complicated with heart failure

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【作者】 王明军云美玲刘正旺郑磊

【Author】 WANG Ming-jun,YUN Mei-ling,LIU Zheng-wang,et al.(Affiliated Hospital of Hainan Medical College,Haikou 570102,Hainan,P.R.China)

【机构】 海南医学院附属医院贵阳中医学院海南省中医院

【摘要】 目的观察螺内酯联和芪参益气滴丸治疗扩张型心肌病合并心力衰竭的疗效。方法选取扩张型心肌病并心力衰竭患者120例,随机分为两组(对照组和治疗组),每组60例,对照组患者全部给予常规治疗,治疗组在常规治疗基础上,加服螺内酯片和芪参益气滴丸,3个月后观察疗效。比较分析两组患者治疗前后疗效和心功能参数,包括左室射血分数(LVEF)、左室舒张末横径(LVDd)。结果两组心功能疗效分析,治疗组总有效率为95.0%,而对照组总有效率为75.0%,治疗组明显优于对照组(P<0.05)。结论螺内酯联合芪参益气滴丸治疗扩张型心肌病,能明显改善患者症状。

【Abstract】 Objective To observe the clinical effect of spironolactone combined with Qishenyiqi pills on dilated cardiomyopathy cases complicated with heart failure. Methods The 120 dilated cardiomyopathy cases complicated with heart failure were selected and randomly divided into the treatment group and the control group each consisted of 60 cases.The cases in control group were treated with the conventional methods.Based on the conventional anti-heart failure treatment,those in treatment group were orally given spironolactone combined and Qishenyiqi pills.The curative effects and the cardiac function parameters before and three months after treatments were compared between the two groups,including left ventricular ejection fraction(LVEF),left ventricular end-diastolic dimension(LVED). Results With regard to the cardiac function,the total effective rate was 95.0% in the reatment group and 75.0% in the control group showing that the treatment group was significantly superior to the control group in the improvement of the cardiac function. Conclusion Spironolactone combined with Qishenyiqi pills could significantly relieve the symptoms of the patients with dilated cardiomyopathy.

【基金】 海南省自然科学基金项目(No.309039);海南省教育厅重点科研资助项目(No.HjKj2009-53)
  • 【文献出处】 中国热带医学 ,China Tropical Medicine , 编辑部邮箱 ,2013年04期
  • 【分类号】R542.2
  • 【被引频次】4
  • 【下载频次】113
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