【摘要】 目的调查性别因素对反流性食管炎(RE)患者的影响。方法 2009年1—4月在我科行内镜检查证实为RE的患者263例,根据男女分组,进行中国版反流病问卷(RDQ)调查。对主要症状的严重程度和发生频率、次要症状及伴随症状进行统计分析,并对男女患者的RDQ积分与RE的严重程度相关性进行分析。结果 (1)RE患者共263例,其中男性在例数上多于女性(165∶98),男性RDQ积分低于女性,差异有统计学意义(P<0.05)。(2)女性RE患者吞咽困难、咽部异物感、早饱和便秘的发生率均较男性高,且差异有统计学意义(P<0.05)。(3)女性胃灼热、胸痛、反酸、反食严重程度和频率积分均高于男性,差异有统计学意义(P<0.01)。(4)男性RE患者与女性RE患者的RDQ积分及RE的严重程度均无直线相关性(r=-0.002,P=0.997;r=-0.1444,P=0.157)。结论 RE患者中,女性的RDQ积分高于男性,女性自觉症状较男性严重。更多还原

【Abstract】 Objective To investigate the role of gender factor in reflux esophagitis( RE) patients. Methods Totally 263 RE patients diagnosed by endoscopy were divided into groups male and female to perform RD questionnaire( RDQ). The severity and occurrence frequency of the main symptoms,minor and simultaneous symptoms were analyzed statistically and RDQ scores and RE severity analyzed correlatedly. Results( 1) There were 263 RE patients altogether,thereinto,case number was more in males( 165,62. 7%) than in females( 98,37. 3%),refluxing scores were lower,the difference was significant( P <0. 05).( 2) Incidences of dysphagia,pharyngeal foreign body sensation,satiety and constipation were higher in female RE patients than in male,the difference was significant( P < 0. 05).( 3) In the comparison of scores of degree and occurrence frequency of the main symptoms,the symptoms of heartburn,chest pains,sour regurgitation,food regurgitation were higher in females than in males,the difference was significant( P < 0. 05).( 4) RDQ score was not correlated with severity of esophagitis in both male and female RE patients( r =- 0. 002,P = 0. 997; r =- 0. 1444,P = 0. 157). Conclusion In RE patients,RDQ score is higher and subjective symptoms severer in females than in males.更多还原