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2011年我院药品不良反应570例分析

Analysis of 570 cases of adverse drug reaction in our hospital in 2011

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【作者】 钱向英陆敏汪宇支敏倩

【Author】 QIAN Xiang-ying,LU Min,WANG Yu,et al.The Second People’s Hospital of Changshu City,Changshu,Jiangsu 215500,China

【机构】 江苏省常熟市第二人民医院药学部

【摘要】 目的了解该院药品不良反应(ADR)发生的特点及规律,促进临床合理用药。方法采用回顾性分析方法 ,对该院2011年收集的570份ADR报告进行统计、分析。结果≥60岁的老年患者发生ADR的频率最高[191例(33.51%)],静脉给药引发的ADR最多见[527例(92.46%)],ADR涉及的药品以抗感染药物居首位[298例(52.28%)],ADR累及的器官/系统以皮肤及其附件损害最常见[339例(59.47%)]。结论临床应重视并加强ADR监测,促进合理用药,尽量避免或减少ADR的发生。

【Abstract】 Objective To investigate the characteristics and regularity of adverse drug reaction (ADR) in our hospital to promote a rational clinical drug use.Methods By retrospective study method,570 ADR cases from our hospital in 2011 were analyzed statistically.Results ADR mostly occurred in patients aged above 60 years old (191 cases,33.51%).ADR cases were mostly caused by intravenous administration (527 cases,92.46%).Antimicrobial drugs took up the first place among ADR-inducing drugs (298 cases,52.28%).Lesion of skin and appendants were the most common clinical manifestations(322 cases,56.49%).Conclusion Great importance should be attached to ADR monitoring and rational drug use to reduce or avoid the occurrences of ADR.

【关键词】 药品不良反应报告合理用药
【Key words】 Adverse drug reactinoReportRational drug use
  • 【文献出处】 临床合理用药杂志 ,Chinese Journal of Clinical Rational Drug Use , 编辑部邮箱 ,2013年02期
  • 【分类号】R97
  • 【被引频次】12
  • 【下载频次】26
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