【摘要】 钙磷代谢紊乱及骨病是慢性肾功能不全特别是透析患者的重要并发症之一。肾性骨病发病机制较为错综复杂,主要为钙磷代谢紊乱、活性维生素D缺乏、继发性甲状旁腺功能亢进等。其临床治疗手段较多,目前已开发的多种新药针对肾性骨病病理生理的多个环节进行干预。降钙素可有效减少维持性透析患者的骨量丢失,降低PTH水平,改善临床症状,改善钙在骨的沉积,增加骨密度,其在肾性骨病的治疗,还需进一步研究证实。更多还原

【Abstract】 Calcium phosphorus metabolism disorders and bone disease is chronic renal insufficiency of dialysis patients,especially one of the important complications.Renal sexual bone disease pathogenesis is relatively complex,mainly for calcium phosphorus metabolism disorder,active vitamin D deficiency,secondary hyperparathyroidism and so on.The clinical treatment means more,currently has a variety of new drug development for renal sex osteopathy pathophysiologic multiple links to intervene.Calcitonin can effectively reduce the maintenance dialysis patients bone loss,reduce the level of PTH,improve clinical symptoms and the calcium in bone deposition and increase the bone density.The renal sex osteopathy treatment,still need further study confirmed.更多还原