【摘要】 目的探讨头孢菌素类药物结晶所致急性肾功能衰竭的诊断及治疗方法。方法回顾性分析17例头孢菌素类药物结晶致上尿路急性梗阻患者的临床资料,采用输尿管镜下气压弹道或钬激光击碎药物结晶并置入双"J"管。所有病例动态监测血肌酐(Cr)和尿素氮(BUN)。结果 15患者术后多尿期明显,血肌酐、尿素氮呈进行性下降趋势,术后3～7 d所有患者血尿素氮、血肌酐基本恢复正常。结论早期正确诊断是治疗头孢菌素类药物结晶致上尿路急性梗阻的首要环节,及时行输尿管镜诊疗技术具有安全、有效、微创等优点。更多还原

【Abstract】 Objective To investigate the diagnosis and treatment of acute renal failure caused by cephalosporins crystal.Methods The clinical data of 17 patients with acute upper urinary obstruction secondary to cephalosporins crystal managed by pneumatic or holmium laser lithortripsy under ureteroscope followed by placement of double J stent were retrospectively analyzed.Serum Cr and BUN were detected in all patients.Results Significant polyuria stage was noted in15 patients.Serum Cr and BUN kept decreasing and reached normal range within3～7 days postoperatively.Conclusions Early diagnosis is key to cure acute upper urinary obstruction caused by cephalosporins crystal.Treatment with ureteroscopic modalities are safe,effective and minimally invasive.更多还原