【摘要】 目的:分析新疆维吾尔族恶性黑素瘤的病理学特征。方法:收集26例新疆维吾尔族恶性黑素瘤,采用HE染色和免疫组化标记,进行病理分析。结果:恶性黑素瘤的组织结构及病理形态复杂多样性,以多种细胞类型和组织形态混合存在为主要特征,细胞类型可分为:上皮样细胞型、梭形细胞型、小痣样细胞型、气球样细胞型、混合型。免疫组化标记瘤细胞表达HMB-45、S-100、Ki-67、Vim-entin、Melan-A分别为90%、100%、100%、90%、96%。结论:恶性黑素瘤临床表现复杂,其诊断及鉴别诊断主要依靠病理学、免疫组化检查。更多还原

【Abstract】 Objective:To analyze the pathological features of malignant melanoma of Xinjiang uygur.Methods: the pathological features were analyzed after HE staining and immunohistochemistry in 26 patients with malignant melanoma.Results:The histopathologjcal structures and morphological characteristics of malignant melanoma were complex.The main features of melanoma under light microscopy showed a variety of histological features,including epithelioid cell type,spindle cell type,nevus - like cell type,hylocyte cell type and mixed cell type.The immuno-histochemistry showed that the positivity rates of HMB - 45,S - 100,Ki - 67,Vimentin,Melan - A were 90%, 100%,100%,90%and 96%respectively.Conclusion:The melanoma has a variety of clinical manifestations and the diagnosis mainly depends on histopathological and immunohistochemistry findings.更多还原