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虚汗停颗粒治疗自汗盗汗临床疗效及安全性荟萃分析

Randomized Controlled Trials of Xuhanting Granules for Spontaneous and Night Aweat:A Meta-Analysis

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【作者】 夏伟卢磊邱勇李家岭赵光王忠良张阳杨关林张义勤

【Author】 XIA Wei1,LU Lei1,QIU Yong1,LI Jialin1,ZHAO Guang1,WANG Zhongliang1, ZHANG Yang2,YANG Guanlin3,ZHANG Yiqin1(1.Xuzhou Hospital of Traditional Chinese Medicine,Xuzhou 221000,Jiangsu,China;2.Affiliated Hospital of Liaoning University of Traditional Chinese Medicine,Shenyang 110032,Liaoning,China;3.Liaoning University of Traditional Chinese Medicine,Shenyang 110847,Liaoning,China)

【机构】 徐州市中医院辽宁中医药大学附属医院辽宁中医药大学

【摘要】 目的:评价虚汗停颗粒治疗自汗盗汗的临床疗效及安全性,提供循证医学证据。方法:检索了最新国内外虚汗停颗粒临床试验报告文献。2名研究人员独立提取研究资料,且交叉核对,软件Review Manager 5.1软件由Cochrane协作网提供。结果:4篇随机对照试验满足纳入标准和排除标准,共治疗849例患者。治愈率研究之间无明显异质(χ2=5.36,df=3,P=0.15>0.1),有效率的OR=1.78和95%CI(1.29,2.45),临床疗效和症状改善差异有统计学意义(P<0.00001)。结论:虚汗停颗粒对其临床疗效及症状改善荟萃分析显示,疗效确切,值得推广。

【Abstract】 Objective:To evaluate the efficacy and safety of Xuhanting Gruanles for spontaneous and night sweat so as to provide evidence-based medicine.Methods:We reviewed the recent literature both at home and abroad about clinical trials on the efficacy and safety of Xuhanting Granules.The research data was retrieved by 2 review authors independently and which were analyzed statistically using Review Manager 5.1 software provided by the Cochrane Collaboration network.Results:A total of 4 randomized controlled trials(RCTs)involving 849 cases met the inclusion criteria,there was no significant heterogeneity between Xuhanting Granules group and control group(χ2=5.36,df=3,P=0.15),OR=1.78 [95%CI(1.29,2.45)].Therefore,the fixed effect model analysis was available;the efficacy showed statistically significant differences(P<0.00001).Conclusion:The Meta-analysis revealed that Xuhanting Granules is effective for spontaneous and night sweat and the differences were of statistical significance.

【基金】 辽宁省科技厅科学技术计划项目(2010225034)
  • 【文献出处】 辽宁中医药大学学报 ,Journal of Liaoning University of Traditional Chinese Medicine , 编辑部邮箱 ,2013年09期
  • 【分类号】R286.0
  • 【被引频次】6
  • 【下载频次】346
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