【摘要】 目的:比较中药疏肝活络养阴法和氟哌啶醇治疗儿童多发性抽动症的临床疗效。方法:将108例儿童多发性抽动症患儿随机分为中药治疗组54例和西药对照组54例,中药治疗组每次50~100ml,1日3次,每日1剂;西药对照组口服氟哌啶醇治疗,2组均治疗8周。按照耶鲁综合抽动严重程度量表(YGTSS)标准进行疗效评价,并观察治疗前后疗效及。结果:两组治疗前后自身对照YGTSS评分比较差异有统计学意义(P<0.05),组间比较差异无统计学意义(P>0.05)。两组疗前疗后用尼莫地平法评分,中药治疗组总有效率为87.04%,西药对照组总有效率为83.33%,2组间疗效对比差异无统计学意义(P>0.05)。结论:中药疏肝活络养阴法治疗儿童多发性抽动症较之西药氟哌啶醇可取得相当的临床疗效,鉴于西药氟哌啶醇副作用较大,笔者建议可在临床上使用中药疏肝活络养阴法治疗本病。更多还原

【Abstract】 Objective: To compare the clinical curative effect of Haloperidol and the Chinese herbs of soothing the liver, activating collterals and nourishing Yin on children with Tourette syndrome. Methods:108 cases of children with Tourette syndrome were randomly divided into treatment group(54 cases), received Chinese herbs decoction, and control group(54 cass), received oral haloperidol. Yale YGTSS was used to evaluate the treatment effect. Results: YGTSS rating of both groups before and after treatment had significant difference(P < 0.05),but no significant difference was found between the two groups after treatment(P>0.05). The total effective rate of the treatment group and control group was 87.04% and 83.33%, with no significant difference. Conclusion:Chinese medicine and Western medicine haloperidol in the treatment of Tourette syndrome in children may make comparable clinical efficacy, but the clinical side effects of Chinese medicines are significantly less than haloperidol,which is worth to be recommended.更多还原