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不同紫外光源对光斑贴试验的光变应原检出率的影响

Effect of Different Ultraviolet Light Source on Photo-allergen Detection Rate in Photopatch Test

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【作者】 许教雄杨文林杨健熊峰史毓杰

【Author】 XU Jiao-xiong,YANG Wen-lin,YANG Jian,XIONG Feng,SHI Yu-jie(Department of Dermatology,The Second Affiliated Hospital of Guangzhou Medical University,Guangzhou 510260,China)

【机构】 广州医学院第二附属医院皮肤科

【摘要】 目的:研究不同紫外光源对光斑贴试验的光变应原检出率是否存在差异。方法:对35例有光敏反应疑为光变应性接触性皮炎且符合入选标准的患者,应用国际标准光斑贴系列SP-1000变应原进行光斑贴试验,采取自身对照方法在试验中分别采用UVA+UVB和单纯UVA作为照射光源进行检测,比较其检测结果的差异。结果:接受光斑贴试验的35例患者中采用UVA+UVB照射检出阳性光变应原19项次(2.71%);采用单纯UVA照射检出阳性光变应原11项次(1.57%);UVA+UVB组变应原阳性检出率高于单纯UVA组,差异有统计学意义(2=6.13,P<0.05)。结论:光斑贴试验采用UVA+UVB作为检测光源优于单纯UVA,可减少漏诊。

【Abstract】 Objective:To investigate the difference of photo allergen positive rate between different ultraviolet light source using for photopatch test.Methods:Thirty-five patients suspected as photoallergic contact dermatitis were performed photopatch test with the SP-1000 standard series of allergens by self-control method.Both UVA+UVB and UVA were respectively used as the irradiation light source in photopatch test,the difference in positive rate of photo allergen between two groups was compared.Results:There were 19 positive reaction items(2.71%) in UVA+UVB group,and 11 positive reaction items(1.57%) in UVA group.The positive reactions items in UVA+UVB group was higher than that in UVA group(χ2=6.13,P<0.05).Conclusion:UVA+UVB used as the irradiation light source in the photopatch test can improve the positive rate of photo allergen and reduce misdiagnosis.

【关键词】 光斑贴试验光变应原长波紫外线中波紫外线
【Key words】 Photopatch testPhoto allergenUVAUVB
  • 【文献出处】 皮肤性病诊疗学杂志 ,Journal of Diagnosis and Therapy on Dermato-venereology , 编辑部邮箱 ,2013年03期
  • 【分类号】R758.22
  • 【被引频次】3
  • 【下载频次】48
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