【摘要】 目的:了解SAPHO综合征的临床特征,提高对本病的认识。方法:对5例SAPHO患者的相关资料进行总结分析。结果:5例患者男女发病比例相当,表现为不同程度的皮肤、骨和关节改变,以前胸壁、胸锁关节和脊柱受累为主,前胸壁、胸锁关节等X线检出阳性率为80%(4/5),CT检出阳性率达到100%(3/3)。脊柱行CT检查和MRI检查的患者均有阳性病变。结论:SAPHO综合征容易误诊,影像学检查是必要的。早期进行治疗可以有效减轻症状,干预病变进展。更多还原

【Abstract】 Objective:To investigate the clinical characteristics of synovitis-acne-pustulosis-hyperostosis-osteitis syndrome(SAPHO) and to improve the understanding of SAPHO syndrome.Methods:Relative data on 5 cases of SAPHO were analysized and summarized.Results:The clinical manifestations were different degree changes of skin,bones and joints.The main pathological changes were seen in anterior chest wall,sternoclavicular joint and spine.The positive rates of X ray were 80%(4/5)and 100%(3/3) of CT on positions such as anterior chest wall and sternoclavicular joints.There were positive changes on CT and MRI of the spine.Conclusion:It is easy to misdiagnose SAPHO syndrome in clinics and it is necessary to develop imaging examinations.It is possible to reduce clinical symptoms and slow the progress through early treatment.更多还原