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急性心肌梗死患者超敏C反应蛋白和N末端-脑钠肽前体的临床观察

Clinical Observation of High Sensitivity C-reactive Protein and N-terminal Pro-brain Natriuretic Peptide in Patients with Acute Myocardial Infarction

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【作者】 吴红栋吴莎莎张研李政朱卫民石理

【Author】 WU Hong-dong;WU Sha-sha;ZHANG Yan;LI Zheng;ZHU Wei-ming;SHI Li;Department of Emergency,the Affiliated Zhuhai Hospital of Jinan University;

【机构】 暨南大学附属珠海医院急诊科

【摘要】 目的:探讨急性心肌梗死(AMI)患者急性期超敏C反应蛋白(hs-CRP)和N-末端脑钠肽前体(NTproBNP)水平及其临床意义。方法:将AMI患者76例分为ST段抬高急性心肌梗死(STEMI组,n=53)和非ST段抬高急性心肌梗死(NSTEMI组,n=23),并以健康者对照(C组,n=20),就诊时立即检测血浆hs-CRP浓度和NTproBNP水平。结果:STEMI组血浆hs-CRP、NT-proBNP均显著高于NSTEMI组和对照组(P<0.01)。结论:AMI患者血浆hs-CRP和NT-proBNP水平在急性期显著升高,并与心肌缺血的严重程度相关。

【Abstract】 Objective:To explore the levels and clinical significance of high sensitivity C-reactive protein(hs-CRP)and plasma N-terminal pro-brain natriuretic peptide(NT-proBNP) in patients with acute myocardial infarction(AMI).Methods:76 patients with AMI were divided into STEMI group(n =53) and NSTEMI group(n =23),while healthy adult as control group(n=20).hs-CRP and NT-proBNP were measured immediately after the patients with AMI arriving the emergency room.Results:Compared with the control group and NSTEMI group,plasma hs-CRP,NT-proBNP significantly increased in STEMI group(P<0.01).Conclusion:The hs-CRP and NT-proBNP elevated on the early stage in patients with AMI,and had a positive correlation to the degree of the myocardial ischemia.

  • 【文献出处】 岭南急诊医学杂志 ,Lingnan Journal of Emergency Medicine , 编辑部邮箱 ,2013年04期
  • 【分类号】R542.22
  • 【下载频次】30
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