【摘要】 目的 探讨放疗联合化疗对局限期小细胞肺癌时放疗的时机选择。方法 将将72例局限期小细胞肺癌患者随机分为A、B、C、D四组,各18例,分别于化疗1个周期、2个周期、3个周期后及化疗结束后进行放疗,观察各组的疗效及不良反应。结果 A组治疗效果最佳,但不良反应剧烈,D组不良反应最低,但治疗效果不及其他三组,C组在获得良好治疗效果的同时不良反应患者能够耐受。结论 治疗局限期小细胞肺癌化疗3个周期后进行放疗时机最佳。更多还原

【Abstract】 Objective To find the optimal timing to add the radiotherapy in the treatment for limited-stage small cell lung cancer.Methods Divided the patients into four groups(A、 B、 C and D),all of the patients received the chemotherapy first,than had the radiotherapy in the treatment after the first cycle(Group A) 、 the second cycle(Group B) 、 the third cycle(Group C) and the fourth cycle(Group D) respectively.The efficacy were observed after the treatment of the two groups as well as the occurrence of adverse reactions.Results The Group A had the best efficay,but at the same time the adverse reactions were severe;Group D had the lowest strength of the adverse reactions,but the efficacy was not as good as another groups;Group C had a low strength of the adverse reactions as well as the good efficacy.Conclusion The optimal timing to add the radiotherapy in the treament for limited-stage small cell lung cancer is after the moment of the third cycle of the chemotherapy.更多还原