【摘要】 目的 研究内镜下应用多环黏膜切除术(multiband mucosectomy,MBM)治疗Barrett食管。方法 采用前瞻性研究的方法,在窄波成像(narrow band imaging,NBI)下确认Barrett食管病变范围,用多环黏膜切除器吸引病灶,套扎橡皮圈后用圈套器电切。3个月复查胃镜,评估疗效。结果 134例Barrett食管患者共切除病灶206块。急性并发症出血发生率6.7%(9/134),无一例发生穿孔。术后30d内(迟发性并发症)出血发生率1.5%(2/134),出现食管狭窄症状39.8%(53/133);30d后(远期并发症)主要为食管狭窄,发生率2.3%(3/133)。术后3个月复查胃镜,病灶完整切除率98.5%(131/133)。结论 内镜下MBM术治疗Barrett食管,简便、安全、有效。更多还原

【Abstract】 Objective We studied the method of multiband mucosectomy(MBM) for endoscopic treatment of Barrett esophagus.The aim was to evaluate the safety and efficacy of the MBM for complete endoscopic removal of Barrett’s esophagus.Methods Prospective registration of all MBM procedures in Barrett’s esophagus was carried out between June 2011 and October2012 in our hospitals.Prior to MBM,the target area was delineated with narrow band imaging(NBI).The delineated area was completely resected by MBM..Endoscopy was re-checked in 3 months to evaluate.Result A total of 206 MBM procedures were performed in 134 patients.The only acute complication was bleeding(in 6.7%,endoscopically managed).There was no perforation occurred despite absence of submucosal lifting.Early complications consisted of delayed bleeding(in 1.5%,endoscopically managed) and stenosis which occurred in 39.8%of patients(most managed by medicine).There are 2.3%of patients who were treated in a(stepwise) radical resection protocol occurred the long-term complication of stenosis.Complete endoscopic resection was achieved in 98.5%of the study.Conclusion MBM is a safe and effective technique for treatment in Barrett’s esophagus.更多还原