Objective To investigate the clinical features,treatment and prognosis of drug-resistant gestational trophoblastic neoplasia(GTN).Methods The clinical data of 15 GTN patients was retrospectively analyzed.Results The 15 cases of drug-resistant GTN were mainly treated by chemotherapy.Among them,there were 10 cases treated by chemotherapy and 5 cases treated by chemotherapy combined with operation.When treatment finished,12 cases got serologically complete remission and 3 were partial remission,respectively.Th...