【摘要】 目的应用相干光断层扫描(OCT)探讨视网膜中央动脉阻塞(CRAO)的图像特征及进行视力相关因素分析。方法用OCT对发病3 d内CRAO进行经中心小凹的水平和垂直扫描,记录OCT图像特征,并测量黄斑中心凹区视网膜厚度、黄斑中心凹区光感受器宽度、视网膜神经上皮层厚度,运用双变量相关分析,比较最小分辨角对数(logMAR)视力与黄斑中心凹区视网膜厚度、黄斑中心凹区光感受器宽度、视网膜神经上皮层(RNL)厚度的关系。结果 CRAO的OCT图像特征主要表现为光感受器暗区宽带增大,RNL增厚,黄斑中心凹色素上皮层高反射区,CRAO患者黄斑中心凹区视网膜厚度与logMAR视力相关性不显著(r=0.314,P﹥0.05);CRAO患者RNL厚度但与logMAR视力相关性不显著,(r=-0.221,P﹥0.05);CRAO患者黄斑中心凹区光感受器宽度明显增宽,与logMAR视力呈显著正相关(r=0.633,P<0.01)。结论 OCT技术可以清晰观察CRAO患者各层视网膜结构,黄斑中心凹区光感受器宽度与中心视力间存在一定的相关性。更多还原

【Abstract】 Objective To investigate the morphologic changes of central retina in central retinal artery occlusion(CRAO) using optical coherence topography(OCT),and to correlate the OCT imaging features with visual acuity outcomes.Methods Seventeen patients(17 eyes) with CRAO were examined with OCT within 3 days from diagnose.The scanning was focused on horizontal and vertical planes crossing the fovea.Foveal thickness,photoreceptor width,and retinal nerve layer(RNL) thickness were measured.The correlation between these measurements and logMAR visual acuity was analyzed.Results The OCT imaging features in CRAO include increased RNL thickness,high foveal reflex,and large photoreceptor width.The correlation between logMAR and the foveal thickness is not significant(r=-0.221,P>0.05).The correlation between RNL thickness and logMAR is slightly higher but not significant(P>0.05).There was a significant positive correlation between the photoreceptor width and logMAR(r=0.633,P<0.01).Conclusions OCT can clearly demonstrate the retinal changes in CRAO.There is a moderate correlation between the photoreceptor width and the logMAR visual acuity.更多还原