【摘要】 目的探讨直肠鳞状细胞癌(squamous cell cancer,SCC)采用同步放化疗治疗的可行性。方法回顾性分析我院1999—2010年经同步放化疗治疗的直肠SCC 5例的临床资料。结果本文5例均采用分次外照射放疗联合同步化疗。4例完成治疗后8周临床评估达完全缓解;1例可疑局部残留,行手术治疗,术后病理检查未发现肿瘤细胞。1例临床评估后11个月局部复发,行挽救性腹会阴联合直肠癌根治术。随访2~13年均无肿瘤复发。结论同步放化疗用于直肠SCC的初始治疗是有效及可行的,有助于提高患者的生存质量。更多还原

【Abstract】 Objective To explore the feasibility of synchronal chemoradiation therapy( CRT) in treatment of rectal squamous cell carcinoma( SCC). Methods Clinical data of 5 patients with rectal SCC treated with synchronal CRT from 1999 to 2010 in our hospital was retrospectively analyzed. Results The 5 patients were treated with fractioned external radiation and synchronal chemotherapy. Four patients had complete remission by clinical assessment 8 weeks after treatment; one was suspected with on local residual and received surgical treatment,but no tumor cell was found by postoperative pathological examination. One had local recurrence 11 months after the clinical assessment,and underwent radical correction of remedial coeliac perineum and rectum. There was no neoplastic recurrence with a follow-up for 2-13 years. Conclusion The synchronal CRT in treatment of rectal SCC for initial therapy is effective and feasible,and it is helpful to improve the patients’ quality of life.更多还原