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CHA2DS2-VASc评分法对非瓣膜病性心房纤颤患者继发脑梗死的风险评估作用
Evaluation effects of CHA2DS2-VASc scale on risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction
【摘要】 目的探讨CHA2DS2-VASc评分法对非瓣膜病性心房纤颤(房颤)患者继发脑梗死的风险评估作用。方法分别采用CHADS2和CHA2DS2-VASc评分标准对208例非瓣膜病性房颤患者进行评分,并随访1年观察患者脑梗死的发生率。结果 CHADS2和CHA2DS2-VASc评分法预测房颤患者1年内脑梗死风险的受试者工作曲线下面积(AUCROC)分别为0.66和0.74。CHA2DS2-VASc评分低危组10例患者均未继发脑梗死,中危组28例患者中1例(3.6%)继发脑梗死,高危组170例患者中23例(13.5%)继发脑梗死;3组间脑梗死发生率比较,差异有统计学意义(均P<0.05)。直线回归分析显示,CHA2DS2-VASc评分与房颤患者继发脑梗死呈正相关(r=0.373,P=0.001)。CHA2DS2-VASc评分标准中,不同性别房颤患者继发脑梗死的差异无统计学意义(P>0.05),其余各项差异均有统计学意义(均P<0.05)。结论 CHA2DS2-VASc评分法可较准确评估非瓣膜病性房颤患者继发脑梗死的风险。
【Abstract】 Objective To explore the evaluation effects of CHA2DS2-VASc scale on risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction.Methods Two hundred and eight patients were evaluated by CHADS2 scale and CHA2DS2-VASc scale.The occurrences of cerebral infarction within one year followed up were observed.Results The area under the receiver operative characteristic(AUCROC) of CHADS2 and CHA2DS2-VASc were 0.66 and 0.74 in predicting the risk of cerebral infarction within one year.According to CHA2DS2-VASc criteria,There was no secondary cerebral infarction in low risk group;just one patient(3.6%) had secondary cerebral infarction in medium risk group;while 23 patients(13.5%) had secondary cerebral infarction in high risk group.There were statistical differences in the incidence of cerebral infarction among three groups(all P < 0.05).The linear regression analysis showed that CHA2DS2-VASc score was positive correlation with the occurrence of cerebral infarction in nonvalvular atrial fibrillation patients(r = 0.373,P = 0.001).According to CHA2DS2-VASc criteria,the incidence of cerebral infarction was no statistical difference between different sex patients(P > 0.05),while other score items had statistical differences(all P < 0.05).Conclusion CHA2DS2-VASc scale can effectively predict the risk of nonvalvular atrial fibrillation patients with secondary cerebral infarction.
【Key words】 cerebral infarction; CHA2DS2-VASc scale; nonvalvular atrial fibrillation; risk;
- 【文献出处】 临床神经病学杂志 ,Journal of Clinical Neurology , 编辑部邮箱 ,2013年03期
- 【分类号】R743.3;R541.75
- 【被引频次】35
- 【下载频次】384