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沙美特罗替卡松联合苏黄止咳胶囊治疗咳嗽变异性哮喘疗效观察

Clinical observation of the effect of salmeterol/fluticasone and Su Huang cough relieve capsule in the treatment of 50 patients with cough variant asthma

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【作者】 欧阳晓平吴峰顾扬陶玉坚黄玉民

【Author】 OUYANG Xiao-ping,WU Feng,GU Yang,TAO Yu-jian,HUANG Yu-min Department of Respiratory Medicine,the First Peoples′ Hospital of Yangzhou,Jiangsu 225000,China

【机构】 扬州市第一人民医院呼吸科

【摘要】 目的观察沙美特罗替卡松(舒利迭)联合苏黄止咳胶囊对咳嗽变异性哮喘(CVA)的治疗效果。方法将50例临床诊断为CVA的患者随机分为两组。A:23例,舒利迭(50/250ug)吸入,每日2次。B:27例,舒利迭(50/250μg)吸入,每日2次,同时口服苏黄止咳胶囊3粒/次,每日3次。2周后比较两组患者的咳嗽症状积分和咳嗽敏感性,4周后比较两周患者的复发率。结果 2周后,与A组比较,B组的咳嗽症状积分(P>0.05)无显著差异,而咳嗽敏感性(P<0.05)降低,4周后,B组总复发率较A组下降。结论舒利迭联合苏黄止咳胶囊治疗能降低CVA患者的咳嗽敏感性,减少复发率。

【Abstract】 Objective To investigate the effect of salmeterol/fluticasone and Su Huang cough relieve capsule in the treatment of patients with CVA.Methods 50 patients with CVA were randomly divided into two groups.The group A(n=23) were given 50 μg of salmeterol and 250 μg of fluticasone twice a day.The group B(n=27) were given 3 pills of Su Huang cough relieve capsule once and 3 times a day on the basis of salmeterol/fluticasone(50/250 μg).The cough symptom score and cough reflex sensitivity were compared after 2 weeks and the relapse rate was compared after 4 weeks.Results After 2 weeks,the difference of cough symptom score between the two groups had no statistical significance(P>0.05),but there was significant difference in cough reflex sensitivity between the two groups(P<0.05).The relapse rate of the group B was lower than that of the group A 4 weeks after.Conclusion The combination therapy of salmeterol/fluticasone and Su Huang cough relieve capsule can reduce the cough reflex sensitivity and relapse rate of patients with CVA.

  • 【文献出处】 临床肺科杂志 ,Journal of Clinical Pulmonary Medicine , 编辑部邮箱 ,2013年02期
  • 【分类号】R562.25
  • 【被引频次】20
  • 【下载频次】245
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