【摘要】 目的探讨青年缺血性卒中的危险因素及病因学特点。方法回顾性分析于本院住院治疗的年龄18～50岁青年缺血性卒中患者153例,分析其危险因素、病因学特点、卒中部位、短期预后情况。结果高血压71例(46.4%)、糖尿病42例(27.4%)、高脂血症35例(22.9%)、吸烟11例(7.1%)、酗酒13例(8.4%)为常见的危险因素;经TOAST(Trial of Org 10172in Acute Stroke Treatment)病因学分型,依次为大动脉粥样硬化、小血管闭塞、心源性栓塞、其他已明确的卒中病因及不明病因的卒中。卒中部位均以基底节区多见,伴有多发灶的梗死亦较多见。绝大多数患者短期(发病30天)预后良好。结论高血压、糖尿病、高脂血症、吸烟、酗酒等传统的卒中危险因素仍为青年缺血性卒中主要原因。短期预后大多良好。更多还原

【Abstract】 Objective The aim of this study was to investigate the etiologic spectrum,subtypes and short-term outcomes of ischemic stroke in young adults.Methods We retrospectively reviewed the data of 153 patients aged 18 to 50 with ischemic stroke in a tertiary stoke unit.The risk factors,the distribution of stroke subtype and short-term outcomes were analyzed.Results There were high incidence of hypertension 71 patients(46.4%),diabetes mellitus 42 patients(27.4%),hyperlipidemia 35 patients(22.9%),smoking 11 patients(7.1%) and alcohol abuse 13 patients(8.4%).Large-vessel atherosclerosis was found to be the main subtype of stroke,followed by small-vessel occlusion,cardioembolism,other determined causes,undetermined etiology according to the TOAST(Trial of Org 10172 in Acute Stroke Treatment).Most patients had good outcome in the short-term prognosis(30 days from onset).Conclusion Hypertension,diabetes mellitus,hyperlipidemia,smoking,alcohol abuse and other conventional risk factors are the most common risk factors in the ischemic stroke patients between 18-50 years of age.Short-term outcomes are favorable.更多还原