【摘要】 目的:研究Demirjian法(下文简称"D法")推断南京地区儿童自然年龄的适用性。方法:收集南京医科大学附属口腔医院符合纳入标准的年龄在3～16岁患者的全口曲面断层片共644例,其中男性378例,女性266例。按照D法进行牙龄推断,所得牙龄与自然年龄进行配对t检验,通过建立单因素数学模型探索两者之间的对应关系。结果:直接运用D法对南京地区儿童进行牙龄推断,所得出的结果与实际年龄相比,差异有统计学意义(P<0.01)。建立南京地区儿童牙齿成熟度与自然年龄间的数学模型,得到自然年龄与牙总成熟度的拟合曲线方程:男子组为Y=43.37SIN(0.02579X-1.138)+30.6SIN(0.04275X+0.9984)+3.019SIN(0.08706X+1.649),女子组为Y=55.93SIN(0.04001X-1.642)+90.97SIN(0.05389X+0.7095)+44.25SIN(0.06254X+3.384)。将其推断的年龄与实际自然年龄比较,两者间的差异无统计学意义(P>0.05)。结论:本研究通过建立儿童牙齿成熟度与自然年龄间的数学模型,可以利用牙齿发育程度较为准确推断南京地区3～16岁儿童的自然年龄。更多还原

【Abstract】 Objective:To study the applicability of Demirjian’s method for age estimation in children of Nanjing.Methods:644 panoramic radiographs( 378 boys and 266 girls) which were collected from Affiliated Hospital of Stomatology of Nanjing Medical University were involved in this study with chronological age from 3 to 16 years.Paired t-test was performed between the chronological age and the age determined by Demirjian’s method.Single-factor model was used to explore the relationships of the two kinds of age.Results:For the marked difference between the chronological age and determined age( P < 0.01) ,Demirjian’s method was not suitable to the children in Nanjing.We set up the mathematical model between tooth maturity and natural age of children in Nanjing,then got the curve-fitting equation.For boys:Y = 43.37Sin ( 0.02579X 1.138) + 30.6SIN ( 0.04275X + 0.9984 ) + 3.019SIN ( 0.08706X + 1.649) ,and for girls:Y = 55.93SIN( 0.04001X 1.642) + 90.97SIN( 0.05389X + 0.7095) + 44.25SIN( 0.06254X + 3.384) .The Results of paired t-test between chronological age and predicted age from quadratic equation showed that there was no significant difference in boys and girls( P > 0.05) .Conclusions:Through the establishment of mathematical model between tooth maturity and natural age in this study,we can determine the natural age from 3 to 16 in Nanjing children more accurately by utilizing tooth maturity.更多还原