【摘要】 目的探讨不同糖代谢人群血清SAA、CRP的水平.方法检测糖尿病前期(糖调节受损)以及初诊2型糖尿病患者血清SAA、CRP水平并比较其相关性.结果 (1)IGR组、DM组SAA、CRP水平较正常对照组增加,差异有统计学意义(P<0.05);(2)DM组与IGR组比较,SAA、CRP升高,差异有统计学意义(P<0.05);(3)SAA与CRP呈正相关(r=0.516).结论糖调节受损人群,初诊2型糖尿病患者血清炎症因子水平升高,SAA,CRP均可作为糖代谢紊乱人群有用的预测因子.更多还原

【Abstract】 Objective To investigate the level of serum amyloid A(SAA) and C-reactive protein(CRP) in cases with different glucose metabolism.Methods The level of serum SAA and CRP of the patients with impaired glucose regulation(IGR) and type 2 diabetes mellitus(DM) was detected and compared.Results The SAA and CRP level of IGR and DM was obvious higher than that of normal control group(P<0.05).There was a significant difference of SAA and CRP between DM and IGR(P<0.05).The SAA level of inflammatory cytokines had a positive correlation with CRP.Conclusion The level of inflammatory cytokines is higher in IGR and T2DM,and both SAA and CRP can be used as useful predictors of glucose metabolism disorders.更多还原