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联合应用LDL-C和ABCD2评分预测短暂性脑缺血发作患者短期脑卒中风险

Early stroke risk prediction after transient ischemic attack with LDL-C+ABCD2 score

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【作者】 汪进丁徐丽君万姗姗万和斌张建勋

【Author】 WANG Jinding1,XU Lijun2,WAN Shanshan1,et al.1.Department of Neurology,First People’s Hospital of Jiujiang city,Jiujiang 332000.2.Second Affiliated Hospital to Nanchang University,Jiangxi 330006,China

【机构】 江西省九江市第一人民医院神经内科南昌大学第二附属医院神经内科

【摘要】 目的探讨LDL-C+ABCD2评分法对短暂性脑缺血发作后7 d内发生脑梗死的预测价值。方法用ABCD2评分法和LDL-C+ABCD2评分法分别测定106例TIA患者的评分,并观察TIA后7d内脑梗死的发生率。结果LDL-C+ABCD2评分法和ABCD2评分法的曲线下面积(95%CI)分别为0.849(0.771-0.927)和0.844(0.768-0.920)。采用LDL-C+ABCD2评分中TIA患者中低、中和高危组TIA后7 d内发生脑梗死的比例分别为2.1%、33.3%和64.3%,不同脑卒中风险分层的脑梗死发生率有显著差异(P<0.05)。结论ABCD2评分法是目前临床预测TIA短期进展为脑梗死的有效的方法 ,结合LDL-C检查结果能提高预测的准确性。

【Abstract】 Objective To explore the ability of LDL-C+ ABCD2 score in predicting cerebral infarction of transient ischemic attack(TIA) at 7th day.Methods 106 TIA patients were evaluated according to ABCD2 criteria and LDL-C+ABCD2 criteria.The occurrence of cerebral infarction was observed in 7 days.Results The AUCs(95%CI) of LDL-C+ ABCD2 and ABCD2 were 0.849(0.771-0.927) and 0.844(0.768-0.920).With an LDL-C+ABCD2 score,the 7-day risk of stroke in patients of low risk、moderate risk and high risk was 2.1%、33.3% and 64.3%.The incidence of cerebral infarction of TIA patients with different scores had statistically significant difference(P<0.05).Compared with non-infarction group,the proportions of infarction-patients with LDL-C ≥ 3.10mmol/L are independent risk factors(P<0.05).Conclusion The ABCD2 criteria is effective for predicting the occurrence of cerebral infarction after short time of TIA.and an enhanced accuracy may be expected by LDL-C+ ABCD2 score.

  • 【文献出处】 江西医药 ,Jiangxi Medical Journal , 编辑部邮箱 ,2013年03期
  • 【分类号】R743.34
  • 【被引频次】2
  • 【下载频次】60
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