【摘要】 目的:通过查阅肠道菌群失调患者的病历资料,了解肠道菌群失调的年龄分布、基础疾病、诱因、治疗及预后。方法:采取回顾性调查方法逐个登记。结果:在所有302例患者中年龄大于60岁者77.8%;其中恶性肿瘤患者达32.5%,血液系统疾病患者7.3%,肝硬化患者10.6%,慢性阻塞性肺病患者11.9%,糖尿病患者29例9.6%,脑血管意外患者24例7.9%,慢性心功能不全患者4%,尿毒症患者6.3%,风湿系统疾病患者3.3%;其中使用抗生素者达84.1%;表现为I度菌群失调者14.6%,II度菌群失调者76.8%,III度菌群失调者8.6%;其中94.7%主要表现为腹泄;所有302例患者均使用肠道微生态制剂治疗,1.7%在治疗7天内症状缓解,76.8%治疗8-14天症状缓解,15.9%治疗15-21天症状缓解,1.3%治疗22-30天症状缓解,4.3%患者在治疗期间死亡。结论:年老体弱合并慢性疾病、恶性肿瘤、长期使用广谱抗生素、免疫抑制剂、肾上腺皮质激素者容易发生肠道菌群失调,主要临床症状为腹泻,大部分表现为II度菌群失调,微生态制剂治疗疗效明显。更多还原

【Abstract】 Objective:Through checking my hospital the medical records of diagnosis of intestinal dysbacteriosis (ID), Learn the age distribution, underlying diseases, incentives, treatment and prognosis. Methods: A retrospective study one by one registration. Results: In all 302 patients,More than 60 years old are 77.8%; Patients with malignant tumors are 32.5%, blood diseases are 7.3%, liver cirrhosis are 10.6%, chronic obstructive pulmonary disease are 11.9%,diabetes are 9.6%, cerebral vascular accident are 7.9%, chronic heart failure are 4%, uremia are 6.3%, rheumatoid system disease are 3.3%。In all 302 patients, Patients treated with antibiotics are 84.1%; The patients of grade I are 14.6%, the patients of grade II are 76.8%,the patients of grade III are 8.6%.In all 302 patients, the patients with diarrhea are 94.7%. All patients were treatment with intestinal probiotics, 1.7% patients relieve within 7 days, 76.8% patients relieve within 8-14 days, 15.9% patients relieve within 15-21 days, 1.3% patients relieve within 22-30 days, 4.3% patients died during treatment. Conclusion:Frail elderly with chronic diseases, cancer, long-term use of broad-spectrum antibiotics, immunosuppressants, adrenocorticotropic hormone prone to ID, the main the clinical symptoms are diarrhea, most of the performance of II degree flora, micro-ecological preparations for treatment efficacy.更多还原