【摘要】 氧化偶联反应作为一种高效、经济的C—C键构建策略,在天然产物的全合成中得到了重要的应用.近年来,马大为课题组通过发展高效的LiHMDS/I2偶联条件,成功实现了四种复杂吲哚生物碱的全合成,在该领域取得了重要的进展.本文就马大为课题组近年在该领域的工作作一亮点评述.更多还原

【Abstract】 Oxidative coupling as a highly efficient and economic strategy for carbon-carbon bond formation has been applied in the total syntheses of natural products.Recently,Ma’s group achieved the total syntheses of four complex indole alkaloids by developing a highly versatile LiHMDS/I2oxidative coupling condition,which merits an important progress in this filed.In this highlight,recent progress of Ma’s group is reviewed.更多还原