目的探讨肺功能检查在工业地区不同职业暴露慢性阻塞性肺疾病(chronic obstructive pulmonary disease,COPD)早期诊断的价值及可行性。方法 375例职业暴露职工(职业暴露组)及270例非职业暴露职工(非职业暴露组),检测2组肺活量(vital capacity,VC)、第1秒用力呼气容积(forced expiratory volume in one second,FEV1)、呼气峰流速(peak expiratory flow,PEF)、FEV1/用力肺活量(forced vital capacity,FVC)比值((FEV1/FVC)%),观察肺功能变化及COPD发生率。结果职业暴露组新诊断COPD 42例,患病率为11.2%,非职业暴露组新诊断COPD 18例,患病率为6.7%,2组比较差异有统计学意义(P<0.05);职业暴露组与非职业暴露组VC,FEV1,PEF,(FEV1/FVC)%分别为(3.61±0.91)L与(2.90±0.79)L、(2.98±0.92)L与(2.79±0.52)L、(4.91±2.22)与(3.95±1.84)L、(85.67±13.26...
【英文摘要】
Objective To study the value and feasibility of pulmonary function tests in the diagnosis of chronic obstructive pulmonary disease(COPD) due to occupational exposure in the industrial areas.Methods Occupational exposure group(n=375) and non-occupational exposure group(n=270) were detected pulmonary function and monitored vital capacity(VC),forced expiratory volume in one second(FEV1),peak expiratory flow(PEF),and ratio of FEV1 to forced vital capacity(FVC) to observe the changes pulmonary function and the i...