【摘要】 目的:观察鲨螺硒胶囊(SLX)对免疫低下小鼠免疫功能的影响。方法:把免疫低下的小鼠进行分组对照试验。给药7 d后,观察、统计、分析各种对免疫功能有影响的因素。结果:小鼠灌胃鲨螺硒胶囊0.5 g/kg×7 d。(1)可对抗环磷酰胺(CTX)40mg/kg×3 d引起的胸腺、脾脏指数下降,(2)显著地恢复CTX 15 mg/kg×3 d引起的血清溶血素降低,显著地恢复CTX 40 mg/kg×4 d引起的迟发型超敏反应低下;(3)鲨螺硒胶囊1 g/kg×7 d可提高CTX 25 mg/kg×6 d所致免疫低下小鼠脾淋巴细胞增殖率。结论:该制剂能增强免疫低下小鼠的免疫功能。更多还原

【Abstract】 Objective: To observe the influence on immunosuppression of Shaluoxi Capsule in the mice,the immunity of which is low.Methods: The test was performed by grouping antitheses.And then observe,count and analyze the influence on immune function in 7 days.Results:(1) The thymus and spleen index decline,caused by the CTX with the concentration of 40 mg/kg for 3 days,can be against in mice with intragastric administration of Shaluoxi Capsule with the concentration of 0.5 g/kg;(2) The Serum hemolysin decline and low delayed-type hypersensitivity,caused by CTX with the concentration of 15 mg/kg for 3 days,can be regained in in mice with intragastric administration of Shaluoxi Capsule with the concentration of 0.5 g/kg;(3) The spleen lymphocytes appreciation rate,caused by CTX with the concentration of 25 mg/kg for 6 days,can be improved in mice with intragastric administration of Shaluoxi Capsule with the concentration of 1 g/kg for 7 days.Conclusion :This preparation can enhance immunity is low mice Immunosuppression caused by CTX.更多还原