Objective:To investigate the relationship of the cells Grim-19expression with pathological grade and clinical stage of bladder cancer.Methods:Western blot methods were used to detect the expression of GRIM-19in cancer tissues and para-carcinoma tissue of 50patients with bladder cancer and normal tissues of 38cases.The relationship of these indicators with bladder cancer pathological grade and clinical stage was analyzed.Results:There was significant difference in GRIM-19expression among cancer tissue,para-c...
【基金】
海南省科技厅(811210)~~
【更新日期】
2013-08-27
【分类号】
R737.14
【正文快照】
GRIMs[1](genes associated with ret inoid-IFN-inducedmortality)是最近发现的一群参与干扰素(interferon,IFN)和维甲酸(retinoicacid,RA)合并诱导的细胞凋亡基因,是Kalvakolanu[2]用反义RNA敲除技术在乳腺癌细胞中筛选鉴定并首先报道的凋亡蛋白。Grim-19属GRIMs家族成员,在?