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200例剖宫产抗生素预防性应用的临床研究

Analysis of prophylactic antibiotic application in cesarean section: a clinical report of 200 cases

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【作者】 苏凌春余琳陈素文黎凤彩

【Author】 SU Ling-chun,YU Lin,CHEN Su-wen,LI Feng-cai(Department of Obstetrics and Gynecology,Nanhai District Maternal and Child Health Care of Foshan,Foshan 528200,China)

【机构】 佛山市南海区妇幼保健院妇产科

【摘要】 目的:探讨剖宫产手术不同时期预防性应用抗生素预防术后感染的效果比较。方法:将2012年1月至2012年4月佛山市南海区妇幼保健院产科剖宫产产妇200例随机分为两组,试验组100例,于术前30min、术后立即及术后6 h,分别静脉滴注头孢唑啉钠2 g(0.9%氯化钠液100 ml稀释)。对照组100例,于术后4 h内开始静脉滴注头孢唑啉钠2 g,每天2次,用3 d。观察两组术后体温、血象有无异常升高及术后感染的发生率。结果:试验组术后腹部切口感染率明显低于对照组(P<0.05)。结论:剖宫产术前30 min足量预防性应用一线抗生素头孢唑啉钠是安全、有效的。

【Abstract】 Objective: To investigate the effect of prophylactic application of antibiotic with different treatment methods during perioperative period in cesarean section.Methods: 200 patients were divided into two groups randomly from January to April in 2012.100 cases in experimental group,2.0 g cefazolin was given by adding 0.9% normal saline 250 ml intravenous injected 30 minutes before operation,immediately,and 6 hours after operation,whereas 100 cases in control group 2.0 g cefazolin was given by adding 250 ml 0.9% normal saline intravenously twice per day,a total of 3 days postoperatively.The clinical effect of antibiotic application,including body temperature,white blood cell count,the abdomen margin infection and other aspects were compared between two groups.Results: The ratio of abdomen margin infection was significantly lower in the experimental group than in the control group(P<0.05).Conclusion: It is suggests that using cefazolin to prevent postoperative infection before operation and short course post operation would be effective and safe.

  • 【文献出处】 河南医学研究 ,Henan Medical Research , 编辑部邮箱 ,2013年04期
  • 【分类号】R719.8
  • 【被引频次】3
  • 【下载频次】30
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