【摘要】 目的:探讨促排卵联合PureceptionTM密度梯度法优选精子在AIH中的应用。方法:采用促排卵治疗后,用PureceptionTM密度梯度离心法处理精液,并将优选后的精子应用于AIH治疗周期。结果:精液处理后,精子密度由处理前(47.13±22.97)×109/L提高到(69.32±12.65)×109/L,活率由42.27±12.33%提高到83.20±10.21%,畸形精子率由62.42±23.12%降至38.28±17.24%,差异有显著性。59对夫妇共进行了113个AIH治疗周期,自然周期(33例)AIH妊娠率9.10%,促排卵周期(80例)AIH妊娠率15.00%,差异有显著性。结论:PureceptionTM密度梯度法是一种较好的精子优选方法,联合促排卵治疗可以获得获得较满意的AIH临床妊娠率。更多还原

【Abstract】 Objective To evaluate the efficacy of the combination of PureceptionTM gradient centrifugation techniques for sperm separation and ovarian stimulation in AIH.Methods The semen was prepared by PureceptionTM gradient centrifugation after the ovarian stimulation as a treatment,and the selected sperm suspension was used for AIH.Results After preparation,the density of sperm was increased from(47.13±22.97)×109/L to(69.32± 12.65)×109/L,the motility of sperm was raised from(42.27±12.33%) to(83.20±10.21%) as well,while the abnormal sperm was reduced from(62.42±23.12%) to(38.28±17.24%),the differences were statistical significant(P< 0.01).The study includes 59 infertile couples who received 113 AIH cycles.The clinical pregnant rate per cycle was 9.10% in nature cycles(33 cycles),and 15.00% in ovarian stimulation cycles(80 cycles).Conclusion PureceptionTM gradient centrifugation technique combined with ovarian stimulation in AIH,the clinical pregnant rate is satisfactory.更多还原