【摘要】 目的了解郑州市无偿献血者HCV感染情况,为制定临床用血安全措施提供依据。方法 2011年1月1日至2011年12月31日郑州市163 135名无偿献血者,采用全自动酶标分析系统进行检测,运用Excel 2000统计分析。结果无偿献血者中抗-HCV的阳性率为0.46%,明显低于有偿献血者。抗-HCV阳性率男女差异有统计学意义(x2=8.4256,P<0.05);抗-HCV阳性献血者中ALT升高的只有8.63%,这说明大部分丙型肝炎ALT正常,肝脏并没有受到损伤;抗-HCV和抗-HIV两项均为阳性者有2人。结论应加强无偿献血者的献血前咨询、检测工作,对于高危人群(同性恋、吸毒、卖淫嫖娼)应推迟献血,以确保临床用血安全。更多还原

【Abstract】 Objection To invest the condition of HCV infection among Unpaid Blood Donations in zhengzhou,in order to provide a basis for formulating the policies of clinical use of blood safety.Method 163135 Unpaid Blood Donations in zhengzhou from 2011.1.1 to 2011.12.31,automatic ELISA analysis system was used to test,Excel 2000 was used to statistical analysis.Result The prevalence of anti-HCV positive among Unpaid Blood Donations was 0.46%,significantly lower than that paid donors.The prevalence of anti-HCV positive between male and female was significantly different(x2=8.425 6,P<0.05).Only 8.63% have ALT increased in anti-HCV positive participants,which means most anti-HCV positive participants didn’t have liver damage.2 participants both have anti-HCV and anti-HIV positive.Conclusion Consultation and testing should be strengthen before the donation of Unpaid Blood Donations,the blood donation of high-risk groups(gay,drug abuse and prostitution) should be postponed,in order to ensure that the clinical use of blood safety.更多还原