【摘要】 目的:应用三维斑点追踪成像技术(3D-STE)分析不同构型原发性高血压(EH)患者左心室旋转及扭转特征。方法:将106例EH患者分为4组:左室正常构型(LVN)组(n=30)、向心性重构(CCR)组(n=31)、向心性肥厚(CCH)组(n=29)及离心性肥厚(ECH)组(n=16);选取健康者(n=30)作为正常对照组;测量各组参数:左心射血分数(LVEF)、左室心底水平旋转角度峰值(Prot-B)、心尖水平旋转角度峰值(Prot-A)、整体旋转角度峰值(LVrot)和整体扭转角度峰值(LVtw),比较各组指标间的差异。结果:高血压各组左室心肌质量指数高于正常对照组,且呈递增趋势(P<0.05);与正常对照组、LVN组、ECH组比较,CCR组和CCH组左室后壁舒张末期厚度、室间隔舒张末期厚度、相对壁厚度增高(P<0.05)。正常对照组、LVN组、CCR组与CCH组间LVEF差异无统计学意义(P>0.05),而ECH组的LVEF显著低于其他各组(P<0.05)。与正常对照组比较,LVN组、CCR组、CCH组的Prot-A,Prot-B,LVrot及LVtw均明显增强(P<0.05),3组间呈递增趋势(P<0.05);ECH组的Prot-A,Prot-B,LVrot及LVtw显著低于其他各组(P<0.05)。结论:3D-STE通过评价不同构型EH患者左室旋转及扭转特征,可反映左室收缩功能的改变。更多还原

【Abstract】 Objective:To analyze the characteristics of left ventricular rotation and twist in patients with essential hypertension(EH) of different left ventricular configurations by 3-dimensional speckle tracking echocardiography(3D-STE).Methods:A total of 106 EH patients were divided into 4 groups:a left ventricular normal configuration(LVN) group(n=30),a concentric remodeling(CCR) group(n=31),a concentric hypertrophy(CCH) group(n=29),an eccentric hypertrophy(ECH) group(n=16),and a control group of 30 healthy subjects.The parameters of LVEF,peak basal rotation(Prot-B),peak apical rotation(Prot-A),left ventricular peak apical rotation(LV-rot),and left ventricular peak apical twist(LV-tw) were compared.Results:The left ventricular mass index in the EH groups,which kept increasing,was higher than that in the normal control group(P<0.05).Compared with the normal control group,LVN and ECH group,the left ventricular posterior wall thickness,interventricular septum at end-diastole,and relative wall thickness significantly increased in the CCH and CCR group(P<0.05).LVEF showed no significant difference among the normal control,LVN,CCR and CCH group(P>0.05),but LVEF was lower in the ECH group than in other groups(P<0.05).Compared with the normal control group,Prot-B,Prot-A,LVrot and LVtw were significantly higher in the LVN,CCR and CCH group(P<0.05),but decreased in the ECH group(P<0.05).Conclusion:3D-STE can evaluate the left ventricular rotation and twist in EH patients with different configurations,and reflect changes in the left ventricular systolic function in EH of different configurations.更多还原