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纤维支气管镜刷片和支气管肺泡灌洗术对肺肿瘤诊断敏感性的探讨

Sensitivity of Bronchial Brush and Bronchoalveolarlavage Cytology in the Diagnosis for Lung Tumor

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【作者】 刘秋雨贺慧史玉洁张梦阳王莹刘欣石曼丽

【Author】 Liu Qiuyu;He Hui;Shi Yujie;Zhang Mengyang;Wang Ying;Liu Xin;Shi Manli;Department of Pathology,Henan People’s Hospital;

【机构】 河南省人民医院病理科

【摘要】 目的探讨纤维支气管镜刷片和支气管肺泡灌洗术(BAL)2种细胞学方法诊断肺肿瘤的敏感性,及其中存在的问题。方法对210例肺肿瘤从组织学类型上,分析2种细胞学方法的诊断敏感性,并进行统计学分析;对细胞学诊断阴性的病例分析其相应的原因。结果 210例肺肿瘤中,细胞学诊断阳性率为76.7%(161/210),均较单独刷片(68.6%,144/210)或单独BAL(36.7%,144/210)检查法诊断阳性率高。而细胞量少和细胞退变是导致诊断阴性的最常见原因。结论纤维支气管镜刷片和BAL 2种方法结合能提高阳性诊断率;细胞制片的质量和掌握正确的诊断要点是提高细胞学诊断准确性的关键。

【Abstract】 Objective To evaluate the role of bronchial brushing and bronchoalveolarlavage(BAL) cytology in the diagnosis for lung tumor,and the problems.Methods The 210 patients with lung tumor were retrospectively analyzed both brushing and BAL were performed for all the patients.The sensitivity of the two methods were analyzed and compared with bronchial biopsy,and also the reasons of negative diagnosis were found.Results The sensitivity of only bronchial brushing method,only BAL method and the two methods were 68.6%,36.7% and 76.7%.In every tissue type,the sensitivity of the two methods was higher than that of only one method.The most common reasons of negative diagnosis were few cells and cell regression.Conclusion Bronchial brushing combined with BAL can provide a reliable cytotyping diagnosis.On the other,high quality section and correct diagnosis are important for improving the diagnosed accuracy.

  • 【文献出处】 肿瘤基础与临床 ,Journal of Basic and Clinical Oncology , 编辑部邮箱 ,2013年05期
  • 【分类号】R734.2
  • 【被引频次】7
  • 【下载频次】39
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