【摘要】 褪黑素是松果体腺分泌的活性最高的内源性激素,它在催眠、抗癌、抗衰老等方面起着重要作用。以邻苯二甲酸酐、1,3-二溴丙烷、对甲氧基苯胺为原料,经过取代、缩合、成环、乙酰化等步骤来完成褪黑素(又名脑白金)的合成,探究了其适合的工业合成条件。更多还原

【Abstract】 Melatonin is the highest active endogenous hormone secreted by pineal gland and plays an important role in hypnosis,anti-cancer and anti-aging fields.This article discussed how to produce the hormone using isobenzofuran-1,3-dione,1,3-dibromopropane and 4-methoxybenzenamine as raw materials.The research also explored the ideal reaction conditions in order to apply them to practical industrial production.更多还原