【摘要】 目的:研究危重患者血乳酸水平以及波动情况与死亡率的相关性,指导临床的诊断及治疗,及时准确地判断危重患者的预后。方法:对202例EICU的危重患者行血乳酸水平测定,分别在入住30min内、12h、48h和72h后分别进行血乳酸测定,比较血乳酸水平与死亡率的相关性。结果:危重病患者的死亡危险性与血乳酸浓度有密切相关。危重病组患者血乳酸浓度升高患者的死亡率显著高于正常组(P<0.05);随着血乳酸浓度增高,死亡率从12.67%增加至55.22%(P<0.05),而死亡组患者APACHE II评分分值、血乳酸浓度均明显高于存活组,有统计学意义(P<0.05)。结论:血乳酸浓度与危重病严重程度呈正相关,是危重病预后的敏感的量化指标。更多还原

【Abstract】 Objective: To observe the relationship between changes of blood lactate levels and mortality in critical patients.To guide the clinical diagnosis and treatment,and to predict the prognosis timely and accurately.Method: Dynamic changes of blood lactate in 202 EICU patients at 30min,12 hours,48 hours,72 hours were analysed.Blood lactate level and mortality were campared among these different prognosis.Result: The significant relationship exists between the critical patients’ mortality and the blood lactate concentration.When the blood lactate concentration was elevated in the critical patients’ group,the mortality is significantly higher than the normal patients group(P<0.05).The mortality increased from 12.67% to 55.22%(P<0.05).While the blood lactate levels increased.The APACHE II score and blood lactate concentration in critical patients were significantly higher than the normal group.There’s statistic significance.(P<0.05).Conclusion: The blood lactate concentration is positively correlated with the severity of critical disease,and it will be the sensitive quantification mark for predicting the critical disease’s prognosis.更多还原