【摘要】 目的探讨空腹血糖对急性脑梗塞神经功能及短期预后的影响。方法选取神经内科重症监护室连续住院的81例急性脑梗塞患者为研究对象。根据入院后首次空腹血糖≥7mmol/L定为空腹血糖增高组,空腹血糖<7mmol/L为空腹血糖正常组。检测患者血压、血脂、血清总蛋白(TP)、白蛋白(ALB)等指标,观察空腹血糖≥7mmol/L时患者的神经功能缺损及短期预后情况。结果空腹血糖增高组入院时NIHSS评分(10.71)及出院时NIHSS评分(8.73)均高于血糖正常组(入院时7.2,出院时4.85),P<0.05;空腹血糖增高组死亡率(16.7%)及预后不良发生率(25.0%)均高于空腹血糖正常组(死亡率为7.0%,预后不良发生率为21.1%),但差异无统计学意义。空腹血糖增高组营养不良发生率(62.5%)高于血糖正常组(35.1%),P<0.05。结论急性脑梗塞合并空腹血糖增高患者的神经功能缺损明显加重,营养不良发生率增加。更多还原

【Abstract】 Objective To find out the effect of fasting blood glucose level on neurological function and short-term prognosis in patients with acute cerebral infarction. Methods Eighty-one patients with acute cerebral infarction were enrolled in Neurological Intensive Care Unit (NICU). Based on the fasting blood glucose level, the patients were divided into the increased group (≥7 mmol/L) and the normal group (<7 mmol/L). Blood pressure, blood lipids, total protein (TP), and albumin (ALB) were detected. The neurological functional defects and short-term prognosis were observed when the fasting blood glucose level was higher than 7 mmol/L. Results The NIHSS scores at admission and discharge in the increased group (10.71 and 8.73) were significantly higher than those in the normal group (7.2 and 4.85), P<0.05. The mortality rate and the incidence of poor prognosis were slightly higher in the increased group than the normal group, with no statistically significant difference. The incidence of malnutrition was significantly higher in the increased group (62.5%) than the normal group (35.1%), P<0.05. Conclusion There were aggravated neurological functional defects and higher incidence of malnutrition in the patients of acute cerebral infarction with increased fasting blood glucose level.更多还原