【摘要】 目的观察重症OSAHS患者围手术期使用CPAP的临床疗效。方法将2002年1月~2012年10月在我院住院并行手术治疗的58例已行多导睡眠监测(PSG)的重度OSAHS患者随机分为A、B两组,A组27例患者围手术期未行CPAP治疗,B组31例患者围手术期行CPAP治疗,比较两组患者术前、术后2周、术后半年多导睡眠监测结果(AHI、LSaO2)的变化,及围手术期出现并发症情况。结果两组患者组间AHI、LSaO2比较差异有统计学意义(P<0.05)。术后半年B组AHI、LSaO2较A组疗效显著,差异有统计学意义(P<0.05)。两组患者围手术期出现并发症情况比较,差异有统计学意义(P<0.05)。结论重症OSAHS患者围手术期CPAP治疗能够降低AHI,提高LSaO2,有效减少并发症,疗效显著,值得临床推广。更多还原

【Abstract】 Objective To observe the clinical effect of CPAP for perioperative patients with severe OSAHS.Methods Fifty-eight patients with severe OSAHS underwent operative treatment and polysomnography(PSG)monitoring during January 2002 to October 2012 in our hospital were randomly divided into group A and group B.Twenty-seven patients in group A did not receive CPAP treatment in perioperation, while thirty-one patients in group B underwent CPAP treatment in perioperation. The changes of polysomnography monitoring results(AHI, LSaO2)before the operation and at 2 weeks and half a year after the operation and perioperative complications of two groups were observed and compared. Results There were significant differences in the AHI, LSaO2of each group among at different time(P < 0.05). The AHI, LSaO2at half a year after the operation in group B were significantly better than those in group A, and the differences were significant(P < 0.05). There was significant difference in the perioperative complications between two groups(P < 0.05). Conclusion Perioperative CPAP in the treatment of patients with severe OSAHS can reduce AHI, improve LSaO2, effectively reduce the complications, has significant clinical effect,and it is worthy of clinical application.更多还原