【摘要】 目的探讨分析腹腔镜下肾部分切除术(laparoscopic partial nephrectomy,LPN)在临床上的应用价值及前景。方法从2010年8月~2012年6月,选择40例肾细胞癌患者,年龄35~76岁,平均(53.5±8.0)岁;肿瘤均为早期通过彩超及CT发现,肿瘤直径均在2~5cm之间,平均(3.5±0.8)cm;40例患者随机分为两组,其中A组20例行腹腔镜下LPN(经腹途径),B组20例行腹腔镜下根治性肾切除术(laparoscopic radical nephrectomy,LRN)(经腹途径),术后均随访1年,比较两组患者的术后1年生存率,及术后1年体能状态评分(采用体力状况ECOG评分标准)。结果两组40例患者在术后1年时均存活,两组1年生存率均达到100%;体力状况评分显示A组和B组所有患者均为0分,活动能力正常,与术前差异无统计学意义。结论 LPN在治疗早期肾癌方面,相较于LRN,术后1年时患者生存率及生存状态均无明显差异,具有良好的临床应用前景。更多还原

【Abstract】 Objective To investigate the clinical value and prospects of laparoscopic partial nephrectomy(laparoscopic partial nephrectomy,LPN).Methods From August 2010 to June 2012,40 cases of renal cell carcinoma patients,aged 35-76 years,mean(53.5±8.0) years;tumors were found early by ultrasonography and CT,the tumor diameter between 2-5cm,mean(3.5±0.8) cm.Forty patients were randomly divided into two groups,group A,20 cases of laparoscopic LPN(intraperitoneal),group B 20 patients undergoing laparoscopic radical nephrectomy(laparoscopic nephrectomy,LRN)(intraperitoneal),were followed up after 1 year,two groups were compared after 1 year survival,and postoperative performance status(to adopt Physically ECOG score standard).Results There were 40 patients alive at 1 year postoperatively,the two sets of 1-year survival rate of 100%.Physical status score shwwed all of the patients in group A and group B were zero,activity was normal,and preoperative no difference.Conclusion LPN in the treatment of early stage kidney cancer,compare with LRN,after 1 year patient survival rate and survival status have no significant differences,with good prospects for clinical application.更多还原