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奥拉西坦对高血压脑出血患者认知和生活自理能力的影响效果观察
Effects of oxiracetam on activity of self-care and cognitive function of convalescent patients with hypertensive cerebral hemorrhage
【摘要】 目的探讨奥拉西坦对高血压脑出血患者认知和生活自理能力的影响。方法选取2011年1月~2013年1月我院收治的高血压脑出血患者56例,随机分为观察组和对照组各28例。对照组给予常规药物治疗,观察组在此基础上给予奥拉西坦,比较两组临床疗效。结果观察组患者MMSE评分及Barthel指数评分均显著优于对照组,差异有统计学意义(P<0.05);两组患者在治疗期间均未出现严重不良反应。结论应用奥拉西坦治疗高血压脑出血,可促进患者认知功能和日常生活自理能力的恢复,且安全可靠,值得在临床上应用和推广。
【Abstract】 Objective To explore the effects of using oxiracetam to treat the patients with hypertensive cerebral hemorrhage in self-care ability and cognitive function. Methods Totally 56 cases with hypertensive cerebral hemorrhage in our hospital from January 2011 to January 2013 were selected and randomly divided into observation group and control group,each group contained 28 cases. The control group was given conventional drug, and the observation group was given oxiracetam based on conventional treatment. The clinical efficacy were compared of two groups. Results The scores of MMSE and BI increase significantly in observation group after treatment,compared with those before treatment(P < 0.05).No severe complications were observed of two groups.Conclusion Oxiracetam is effective and safe in improving cognitive function in patients of hypertensive cerebral hemorrhage.It is worth for clinical application and promotion.
【Key words】 Oxiracetam; Hypertensive cerebra1 hemorrhage; Cognitive function; Self-care ability;
- 【文献出处】 中国医药科学 ,China Medicine and Pharmacy , 编辑部邮箱 ,2013年09期
- 【分类号】R743.34
- 【被引频次】5
- 【下载频次】38