【摘要】 多节孢属真菌属粪壳菌纲炭角菌目炭角菌科,种类较多。迄今已报道的次生代谢产物有70多个,包括生物碱、聚酮、萜及甾体等多个类别。多节孢属次生代谢产物多样、丰富,部分具有显著生物活性,如吲哚类生物碱球孢子酸衍生物对埃及伊蚊和丝光绿蝇幼虫有较好的抑制活性,为药物的研发提供了备选化合物,具有潜在开发价值。本文就多节孢属次生代谢产物化学结构及其生物活性的研究进展进行综述,为该真菌资源的开发利用提供参考和依据。更多还原

【Abstract】 The genus Nodulisporium,one of members in Xylariaceae family,produces secondary metabolites with structural diversity.Up to now,more than 70 secondary metabolites have been reported from Nodulisporium sp.,including alkaloids,polyketides,terpenoids,steroids,and so on.Furthermore,some of them display notable bioactivities(for example,nodulisporic acids are obviously active against the larvae of the blowfly and mosquito),which can serve as candidate compounds for developing new drugs.This review presents an overview of the secondary metabolites from Nodulisporium sp.and their bioactivities,in order to provide the basis for exploiting them.更多还原